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PMID: 28121776 PMCID: PMC6939233 DOI: 10. 0000000000000419 Abstract Context: In March 2015, the Virginia Department of Health (VDH) was alerted by the Virginia Poison Center of a 6-patient cluster treated for severe clinical presentations after using heroin. Clenbuterol in the past has been used as an adulterant for heroin. 1 Abuse of clenbuterol may produce hemodynamic compromise, life-threatening dysrhythmias and electrolyte disturbance. Clenbuterol adulteration of heroin has been recognized as a public health problem in the usa (45c, 46a, 47r). Clenbuterol is a long-acting beta2-adrenoceptor He encourages the reader to involve doctors and blood tests, as well as descriptions of individual types of steroids, clenbuterol adulteration. All patients lacked findings of acute clenbuterol toxicity but tested positive for clenbuterol and negative for strychnine and a battery of common potential adulterants. Conclusions: We report five cases of a novel neuromuscular syndrome in users of clenbuterol-adulterated heroin. Clenbuterol is a b2-adrenergic agonist with veterinary uses but is not FDA approved for human use. It is an infrequently reported adulterant in heroin. We describe a recent cluster of. Abstract Background: Adulteration of drugs of abuse may be done to increase profits. Some adulterants are relatively innocuous and others result in significant toxicity
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